Influence of optic disc size on parameters of retinal nerve fiber analysis as measured using GDx-VCC and ECC in healthy subjects.

Hemma Resch (1) , Gabor Deak (2) , Clemens Vass (2)

1 Department of Ophthalmology and Optometry, Medical Universtiy of Vienna
2 Department of Ophthalmology and Optometry,Medical Universtiy of Vienna

Background: To date there is no knowledge about the impact of optic disc size on the retinal nerve fiber layer (RNFL) as measured with GDx VCC or GDx ECC. Since the size of the optic disc is not taken into account for the analyses carried out by the GDx it might affect sensitivity in large optic discs and specificity in small ones. Methods: Topographic optic disc measurements and RNFL thickness values of 80 healthy subjects were measured using HRT3 and GDx VCC and ECC. Subjects were divided into 3 equally large groups depending on optic disc area. We used ANOVA to test the differencs between groups of the GDx VCC and ECC parameters TSNIT average, superior average, inferior average and NFI. Results: The mean optic disc sizes of the three groups were 1.61, 2.00, and 2.61 µm2. The optic disc area significantly affected none of the tested RNFL parameters of the GDx and HRT3. For all HRT3 parameters of optic disc morphology, ANOVA showed statistical significance between the three groups of different optic disc areas. Conclusion: We could not find a significant impact of optic disc size on any RNFL parameter measured with GDx VCC or ECC and with HRT3.

Mots clés: Retina; Optic Nerve; Imaging

Hemma Resch, Gabor Deak, Clemens Vass. Influence of optic disc size on parameters of retinal nerve fiber analysis as measured using GDx-VCC and ECC in healthy subjects.. British Journal of Ophthalmology, 2010, 94 (4), pp.424. ⟨10.1136/bjo.2009.157503⟩. ⟨hal-00557323⟩