CYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity

Henrik Gréen (1) , Karin Skoglund (1) , Franz Rommel (2) , Rajaa A. Mirghani (3, 4) , Kourosh Lotfi (1, 2)

1 Division of Drug Research/Clinical Pharmacology, Department of Medical and Health Sciences, Faculty of Health Sciences
2 Department of Hematology
3 Division of Clinical Pharmacology, Department of Laboratory Medicine
4 Division of Pharmacology, Faculty of Medicine

Mots clés: Chronic myeloid leukemia; Imatinib; CYP3A4; CYP3A5; CGP74588; Complete molecular response

Henrik Gréen, Karin Skoglund, Franz Rommel, Rajaa A. Mirghani, Kourosh Lotfi. CYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity. European Journal of Clinical Pharmacology, 2010, 66 (4), pp.383-386. ⟨10.1007/s00228-009-0772-y⟩. ⟨hal-00553270⟩