Atazanavir plasma concentrations are impaired in HIV-1-infected adults simultaneously taking a methadone oral solution in a once-daily observed therapy setting

Annette Haberl (1) , Manfred Moesch (1) , Gabriele Nisius (1) , Christoph Stephan (1) , Markus Bickel (1) , Pavel Khaykin (1) , Michael Kurowski (2) , Reinhard Brodt (1) , Nils Hentig (1)

1 HIVCENTER, Medical Clinics II
2 HIVLab

Mots clés: Atazanavir; HIV; Low-dose ritonavir; Methadone maintenance therapy; Pharmacokinetics; Protease inhibitor

Annette Haberl, Manfred Moesch, Gabriele Nisius, Christoph Stephan, Markus Bickel, et al.. Atazanavir plasma concentrations are impaired in HIV-1-infected adults simultaneously taking a methadone oral solution in a once-daily observed therapy setting. European Journal of Clinical Pharmacology, 2009, 66 (4), pp.375-381. ⟨10.1007/s00228-009-0767-8⟩. ⟨hal-00550171⟩