From IL-15 to IL-33: the never-ending list of new players in inflammation. Is it time to forget the humble Aspirin and move ahead?

Fulvio d'Acquisto , Francesco Maione , Magali Pederzoli-Ribeil

The study of the inflammatory response has seen a tremendous expansion over the last 30 years. Advancements in technology and better knowledge of the ethiopathogenesis of several inflammatory conditions have facilitated this process allowing researchers to almost reach the core of problem. Thus, we now know that inflammation can be manifested in many different ways depending on the context that has elicited it. Viral and infectious, allergic and autoimmune, carcinogenic and resolutive are just a few examples of how inflammation can disguise itself.

Mots clés: Interleukin-15; Interleukin-17; Interleukin-18; Interleukin-21; Interleukin-22; Interleukin-27; Interleukin-33; resolution of inflammation; autoimmune diseases; antinflammatory drugs

Fulvio d'Acquisto, Francesco Maione, Magali Pederzoli-Ribeil. From IL-15 to IL-33: the never-ending list of new players in inflammation. Is it time to forget the humble Aspirin and move ahead?. Biochemical Pharmacology, 2009, 79 (4), pp.525. ⟨10.1016/j.bcp.2009.09.015⟩. ⟨hal-00544816⟩