A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei

Fernando García-Moreno (1) , María Pedraza (1) , Luca Giovanni Di Giovannantonio (1) , Michela Di Salvio (1) , Laura Lopez-Mascaraque (1) , Antonio Simeone (1) , Juan Andrés de Carlos (1)

1 Molecular, Cellular and Developmental Neurobiology Department

Neurons usually migrate and differentiate within one particular encephalic vesicle. Here we describe a murine population of diencephalic neurons that colonize the telencephalic amygdaloid complex, migrating along a tangential route that crosses a boundary between developing brain vesicles. The diencephalic transcription factor OTP is necessary for this migratory behavior.

Mots clés: Development; Proliferation; •neuroanatomy; •neuroscience

Fernando García-Moreno, María Pedraza, Luca Giovanni Di Giovannantonio, Michela Di Salvio, Laura Lopez-Mascaraque, et al.. A neuronal migratory pathway crossing from diencephalon to telencephalon populates amygdala nuclei. Nature Neuroscience, 2010, ⟨10.1038/nn.2556⟩. ⟨hal-00538625⟩