Age dependency of cerebral P-gp function measured with ()-[C]verapamil and PET

Martin Bauer (1) , Rudolf Karch (2) , Friederike Neumann (2) , Aiman Abrahim (1) , Claudia C. Wagner (1) , Kurt Kletter (3) , Markus Müller (1) , Markus Zeitlinger (1) , Oliver Langer (1, 4, 5)

1 Department of Clinical Pharmacology
2 Department of Medical Computer Sciences
3 Department of Nuclear Medicine
4 Molecular Medicine
5 Department of Clinical Pharmacology, Division of Pharmacogenetics and Imaging

Mots clés: P-glycoprotein; Blood-brain barrier; Age; ()-[C]verapamil; Positron emission tomography

Martin Bauer, Rudolf Karch, Friederike Neumann, Aiman Abrahim, Claudia C. Wagner, et al.. Age dependency of cerebral P-gp function measured with ()-[C]verapamil and PET. European Journal of Clinical Pharmacology, 2009, 65 (9), pp.941-946. ⟨10.1007/s00228-009-0709-5⟩. ⟨hal-00534987⟩