Clinical pharmacology of exogenously administered alkaline phosphatase

P. Pickkers (1) , F. Snellen (2) , P. Rogiers (3) , J. Bakker (4) , P. Jorens (5) , J. Meulenbelt (6) , H. Spapen (7) , J. E. Tulleken (8) , R. Lins (9) , S. Ramael (9) , M. Bulitta (10) , J. G. Hoeven (1)

1 Department of Intensive Care Medicine (551)
2 Department of Anesthesiology
3 Department of Intensive Care
4 Department of Intensive Care
5 Department of Critical Care Medicine and Clinical Pharmacology
6 Division of Intensive Care Centre, University Medical Centre Utrecht, Institute for Risk Assessment Sciences, Utrecht University
7 ICU Department
8 Intensive and Respiratory Care Unit
9 Clinical Pharmacology Unit Antwerp
10 CRM Biometrics GmbH

Mots clés: Alkaline phosphatase; Clinical trial; Inflammation; Volunteer; Sepsis; Renal failure

P. Pickkers, F. Snellen, P. Rogiers, J. Bakker, P. Jorens, et al.. Clinical pharmacology of exogenously administered alkaline phosphatase. European Journal of Clinical Pharmacology, 2008, 65 (4), pp.393-402. ⟨10.1007/s00228-008-0591-6⟩. ⟨hal-00534932⟩