Chiral Memory and Self-Replication Study of Porphyrin and Bilirubin Aggregates Formed on Polypeptide Matrices

Ondrej Julínek (1) , Iryna Goncharova (1) , Marie Urbanová (2)

1 Department of Analytical Chemistry
2 Department of Physics and Measurements

Porphyrin heteroaggregates composed of meso-tetrakis(N-methylpyridinium-4-yl)porphinatocopper(II) and meso-tetrakis(4-sulfonatophenyl)porphyrin formed in the presence of a polyglutamic matrix possess chiral memory and an ability to self-replicate their supramolecular structures. By means of electronic circular dichroism spectroscopy, it has been shown that the self-replication process is not influenced by changes in pH or ionic strength. The average molecular weight of the polyglutamic matrix used for porphyrin aggregate preparation plays a crucial role with regard to the form of the resulting CD spectrum. In the second part of our study, a complex composed of polylysine and bilirubin as a model system for a structured homoaggregate formed on the chiral matrix has been tested for chiral memory phenomena. The results indicate that the bilirubin homoaggregate shows chiral memory.

Mots clés: Physical Sciences

Ondrej Julínek, Iryna Goncharova, Marie Urbanová. Chiral Memory and Self-Replication Study of Porphyrin and Bilirubin Aggregates Formed on Polypeptide Matrices. Supramolecular Chemistry, 2008, 20 (07), pp.643-650. ⟨10.1080/10610270701647919⟩. ⟨hal-00513516⟩