First synthesis of upper rim mono and dinitrone calix[4]arene derivatives

Sofiane Ben Sdira (1) , Roselyne Baudry (1) , Caroline Felix (2, 1) , Marie-Béatrice Giudicelli (1) , Francis Vocanson (1) , Monique Perrin (1) , Roger Lamartine (1)

1 LACE - Laboratoire d'Application de la Chimie à l'Environnement
2 CSAP - Chimie Supramoléculaire Appliquée

A new class of calix[4]arene derivatives bearing one or two nitrone groups on the upper rim has been synthesized using the oxidation of chiral imines with hydrogen peroxide. The imine intermediates were obtained via amination of the diformyl derivative. The 1H NMR spectra and X-ray data indicated a 1,3-disubstituted cone conformation for the imine derivatives and the existence of a single (E,E) isomer. The structural identity of the nitrone derivatives was confirmed from NMR, IR and ES-MS data. Both mono and dinitrone calix[4]arenes were in E configuration.

Mots clés: Physical Sciences

Domaines: Chimie

Sofiane Ben Sdira, Roselyne Baudry, Caroline Felix, Marie-Béatrice Giudicelli, Francis Vocanson, et al.. First synthesis of upper rim mono and dinitrone calix[4]arene derivatives. Supramolecular Chemistry, 2007, 19 (6), pp.393-398. ⟨10.1080/10610270601003932⟩. ⟨hal-00513494⟩