Cultivation of Lacrimal Gland Acinar Cells in a Microgravity Environment

Stefan Schrader (1) , Claudia Kremling (1) , Matthias Klinger (2) , Horst Laqua (1) , Gerd Geerling (3)

1 Department of Ophthalmology, University of Luebeck
2 Department of Anatomy, University of Luebeck
3 JMU - Julius-Maximilians-Universität Würzburg

A Rotary Cell Culture System (RCCS) allows the creation of a microgravity environment of low shear force, high-mass transfer, and 3-dimensional cell culture of various cell types. Aim of this study was to evaluate the growth pattern and the secretory function of rabbit lacrimal gland acinar cells in a microgravity environment using a RCCS.

Mots clés: Tears; Lacrimal gland; Experimental &#8211 laboratory; acinar cells; in vitro; tissue engineering

Stefan Schrader, Claudia Kremling, Matthias Klinger, Horst Laqua, Gerd Geerling. Cultivation of Lacrimal Gland Acinar Cells in a Microgravity Environment. British Journal of Ophthalmology, 2009, 93 (8), pp.1121-n/a. ⟨10.1136/bjo.2008.137927⟩. ⟨hal-00477805⟩