High-Energy Long-Lived Excited States in DNA Double Strands

I. Vaya (1) , F.-A. Miannay (1) , T. Gustavsson (1) , D. Markovitsi (1)

1 LFP - URA 2453 - Laboratoire Francis PERRIN

Dark DNA light: Dark excited states of alternating GC double strands emit fluorescence at 4000 cm-1 higher energy (see spectrum) and with four orders of magnitude longer lifetime compared to the bright * states. Such high-energy long-lived excited states are expected to play a key role in the DNA photoreactivity associated with the appearance of carcinogenic mutations.

Domaines: Chimie théorique et/ou physique

I. Vaya, F.-A. Miannay, T. Gustavsson, D. Markovitsi. High-Energy Long-Lived Excited States in DNA Double Strands. ChemPhysChem, 2010, 11, pp.987 - 989. ⟨10.1002/cphc.201000027⟩. ⟨hal-00472807⟩