Structure, function, and evolution of the Thiomonas spp. genome.

Florence Arsène-Ploetze (1) , Sandrine Koechler (1) , Marie Marchal (1) , Jean-Yves Coppée (2) , Michael Chandler (3) , Violaine Bonnefoy (4) , Céline Brochier-Armanet (4) , ​mohamed Barakat (5) , Valérie Barbe (6) , Fabienne Battaglia-Brunet (7) , Odile Bruneel (8) , Christopher G. Bryan (1) , Jessica Cleiss-Arnold (1) , Stéphane Cruveiller (6) , Mathieu Erhardt (9) , Audrey Heinrich-Salmeron (1) , Florence Hommais (10) , Catherine Joulian (7) , Evelyne Krin (11) , Aurélie Lieutaud (4) , D. Lièvremont (12) , Caroline Michel (7) , Daniel Muller (1, 13) , Philippe Ortet (5) , Caroline Proux (2) , P. Siguier (3) , David Roche (14) , Zoé Rouy (14) , Grégory Salvignol (14) , Djamila Slyemi (4) , Emmanuel Talla (4) , Stéphanie Weiss (1) , Jean Weissenbach (14) , Claudine Médigue (14, 15) , Philippe N. Bertin (1)

1 GMGM - Génétique moléculaire, génomique, microbiologie
2 PF2 - Puces à ADN (Plate-Forme 2)
3 LMGM - Laboratoire de microbiologie et génétique moléculaires - UMR5100
4 LCB - Laboratoire de chimie bactérienne
5 BIAM - Institut de Biosciences et Biotechnologies d'Aix-Marseille (ex-IBEB)
6 IG - Institut de Génomique d'Evry
7 BRGM - Bureau de Recherches Géologiques et Minières
8 HSM - Hydrosciences Montpellier
9 IBMP - Institut de Biologie Moléculaire des Plantes
10 MAP - Microbiologie, adaptation et pathogénie
11 Génétique des Génomes Bactériens
12 DEEGM - Dynamique, évolution et expression de génomes de microorganismes
13 LEM - Laboratoire d'Ecologie Microbienne - UMR 5557
14 UMR 8030 - Génomique métabolique
15 SEG - Structure et évolution des génomes - UMR 8030

Bacteria of the Thiomonas genus are ubiquitous in extreme environments, such as arsenic-rich acid mine drainage (AMD). The genome of one of these strains, Thiomonas sp. 3As, was sequenced, annotated, and examined, revealing specific adaptations allowing this bacterium to survive and grow in its highly toxic environment. In order to explore genomic diversity as well as genetic evolution in Thiomonas spp., a comparative genomic hybridization (CGH) approach was used on eight different strains of the Thiomonas genus, including five strains of the same species. Our results suggest that the Thiomonas genome has evolved through the gain or loss of genomic islands and that this evolution is influenced by the specific environmental conditions in which the strains live.

Domains: Cellular Biology

Florence Arsène-Ploetze, Sandrine Koechler, Marie Marchal, Jean-Yves Coppée, Michael Chandler, et al.. Structure, function, and evolution of the Thiomonas spp. genome.. PLoS Genetics, 2010, 6 (2), pp.e1000859. ⟨10.1371/journal.pgen.1000859⟩. ⟨hal-00463879⟩