Proteins : From Structural Classification to Amino Acid Interaction Networks.

Omar Gaci (1) , Stefan Balev (1)

1 LITIS - Laboratoire d'Informatique, de Traitement de l'Information et des Systèmes

In this paper we introduce the notion of protein interaction network. This is a graph whose vertices are the protein's amino acids and whose edges are the interactions between them. Using a graph theory approach, we identify a number of properties of these networks. Some of them are common to all proteins, while others depend on the structure arrangement. The last group of properties allows to characterize structural classes, defined by CATH or SCOP, in the terms of interaction network properties.

Mots clés: proteins; amino acid; interaction network; structural classification

Domaines: Bio-informatique [q-bio.QM]; Bio-Informatique, Biologie Systémique [q-bio.QM]

Omar Gaci, Stefan Balev. Proteins : From Structural Classification to Amino Acid Interaction Networks.. The 2008 International Conference on Bioinformatics & Computational Biology., Jul 2008, Las Vegas, United States. pp.728-734. ⟨hal-00430627⟩