Multiple-locus variable-number tandem-repeat analysis for rapid typing of Candida glabrata.

Frédéric Grenouillet (1) , Laurence Millon (1) , Jean-Mathieu Bart , Sandrine Roussel (1) , Isabelle Biot , Emeline Didier (1) , Anne-Sophie Ong , Renaud Piarroux (1)

1 LCE - Laboratoire Chrono-environnement (UMR 6249)

A multiple-locus variable-number tandem-repeat analysis (MLVA) using six microsatellite markers was assessed in 127 Candida glabrata isolates. Thirty-seven different genotypes, stable both in vitro and in vivo, were observed. The highest discriminatory power (D = 0.902) was reached by using only four markers. MLVA seems to be relevant for C. glabrata typing.

Domaines: Mycologie

Frédéric Grenouillet, Laurence Millon, Jean-Mathieu Bart, Sandrine Roussel, Isabelle Biot, et al.. Multiple-locus variable-number tandem-repeat analysis for rapid typing of Candida glabrata.. Journal of Clinical Microbiology, 2007, 45 (11), pp.3781-4. ⟨10.1128/JCM.01603-07⟩. ⟨hal-00341434⟩