Microfluidic Device for Continuous Magnetophoretic Separation of Red Blood Cells

Ciprian Iliescu (1) , Elena Barbarini (2) , Marioara Avram (3) , G. Xu (1) , Andrei Avram (3)

1 Institute of Bioengineering and Nanotechnolog
2 Electronics Department
3 National Institute for Research and Development in Microtechnologies

This paper presents a microfluidic device for magnetophoretic separation red blood cells from blood under contionous flow. The separation method consist of continous flow of a blood sample (diluted in PBS) through a microfluidic channel which presents on the bottom “dots” of feromagnetic layer. By appling a magnetic field perpendicular on the flowing direction, the feromagnetic “dots” generates a gradient of magnetic field which amplifies the magnetic force. As a result, the red blood cells are captured on the bottom of the microfluidic channel while the rest of the blood is collected at the outlet. Experimental results show that an average of 95 % of red blood cells are trapped in the device

Domaines: Autre [cs.OH]

Ciprian Iliescu, Elena Barbarini, Marioara Avram, G. Xu, Andrei Avram. Microfluidic Device for Continuous Magnetophoretic Separation of Red Blood Cells. DTIP 2008, Apr 2008, Nice, France. pp.279-281. ⟨hal-00277724⟩