Biodiversité et maladies infectieuses: Impact des activités humaines sur le cycle de transmission des leishmanioses en Guyane

Abstract : The dilution effect hypothesis states that more diverse ecological communities are less prone to pathogen transmission because of the presence of non-competent hosts acting as epidemiological dead-ends. In this work, we investigate the existence of this phenomenon in the case of zoonotic cutaneous leishmaniases in French Guiana. Molecular tools based on high-throughput sequencing technologies have been developed to study the epidemiological system. These tools were employed to explore leishmaniases transmission cycles in forest sites undergoing different levels of human-induced perturbations. Our results seem generally congruent with the dilution effect hypothesis, indicating higher disease risk in the most perturbed site. However, differences observed between sites were not significant, and more data is needed to draw general conclusions.
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Submitted on : Wednesday, April 11, 2018 - 5:21:06 PM
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Arthur Kocher. Biodiversité et maladies infectieuses: Impact des activités humaines sur le cycle de transmission des leishmanioses en Guyane. Santé publique et épidémiologie. Université Toulouse 3 Paul Sabatier (UT3 Paul Sabatier), 2017. Français. ⟨tel-01764244⟩

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