Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6, The Lancet, vol.366, issue.9501, pp.3661960-1963, 2005. ,
DOI : 10.1016/S0140-6736(05)67787-2
URL : https://hal.archives-ouvertes.fr/pasteur-00590989
Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial, The Lancet, vol.369, issue.9560, pp.369491-498, 2007. ,
DOI : 10.1016/S0140-6736(07)60236-0
Artemether-lumefantrine versus artesunate plus amodiaquine for treating uncomplicated childhood malaria in Nigeria: randomized controlled trial, Malaria Journal, vol.5, issue.1, p.43, 2006. ,
DOI : 10.1186/1475-2875-5-43
The Transcriptome of the Intraerythrocytic Developmental Cycle of Plasmodium falciparum, PLoS Biology, vol.280, issue.1, p.5, 2003. ,
DOI : 10.1371/journal.pbio.0000005.st007
Discovery of gene function by expression profiling of the malaria parasite life cycle, Science, issue.5639, pp.3011503-1508, 2003. ,
Tetracyclines Specifically Target the Apicoplast of the Malaria Parasite Plasmodium falciparum, Antimicrobial Agents and Chemotherapy, vol.50, issue.9, pp.3124-3131, 2006. ,
DOI : 10.1128/AAC.00394-06
Mechanisms of gene regulation in Plasmodium, Am J Trop Med Hyg, vol.77, issue.2, pp.201-208, 2007. ,
Plasmodium falciparum : Genome wide perturbations in transcript profiles among mixed stage cultures after chloroquine treatment WHO: Antimalarial drug combination therapy, WHO/CDS/ RBM Geneva, 2001. ,
Artemisinins: activities and actions, Microbes and Infection, vol.6, issue.14, pp.1339-1346, 2004. ,
DOI : 10.1016/j.micinf.2004.09.002
Comparative pharmacokinetics of intramuscular artesunate and artemether in patients with severe falciparum malaria, Antimicrob Agents Chemother, issue.11, pp.484234-4239, 2004. ,
Molecular Factors and Biochemical Pathways Induced by Febrile Temperature in Intraerythrocytic Plasmodium falciparum Parasites, Infection and Immunity, vol.75, issue.4, pp.2012-2025, 2007. ,
DOI : 10.1128/IAI.01236-06
The long and winding road: Protein trafficking mechanisms in the Plasmodium falciparum infected erythrocyte, Molecular and Biochemical Parasitology, vol.147, issue.1, pp.1-8, 2006. ,
DOI : 10.1016/j.molbiopara.2006.01.014
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data, Nucleic Acids Research, vol.31, issue.1, pp.31212-215, 2003. ,
DOI : 10.1093/nar/gkg081
GeneDB: a resource for prokaryotic and eukaryotic organisms, Nucleic Acids Research, vol.32, issue.90001, pp.32-339, 2004. ,
DOI : 10.1093/nar/gkh007
Malaria Parasite Metabolic Pathways ,
Comparative Genomics of Transcriptional Control in the Human Malaria Parasite Plasmodium falciparum, Genome Research, vol.14, issue.8, pp.1548-1554, 2004. ,
DOI : 10.1101/gr.2218604
Protein kinases as targets for anti-parasitic chemotherapy, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, vol.1697, issue.1-2, pp.155-168, 2004. ,
DOI : 10.1016/j.bbapap.2003.11.021
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.333.5861
Chaperoning a cellular upheaval in malaria: Heat shock proteins in Plasmodium falciparum, Molecular and Biochemical Parasitology, vol.153, issue.2, pp.85-94, 2007. ,
DOI : 10.1016/j.molbiopara.2007.01.009
The Hsp40 proteins of Plasmodium falciparum and other apicomplexa: Regulating chaperone power in the parasite and the host, The International Journal of Biochemistry & Cell Biology, vol.39, issue.10, pp.391781-1803, 2007. ,
DOI : 10.1016/j.biocel.2007.02.011
Systems Analysis of Chaperone Networks in the Malarial Parasite Plasmodium falciparum, PLoS Computational Biology, vol.13, issue.9, pp.1701-1715, 2007. ,
DOI : 10.1371/journal.pcbi.0030168.sg004
Oxidative stress in malaria parasite-infected erythrocytes: host???parasite interactions, International Journal for Parasitology, vol.34, issue.2, pp.163-189, 2004. ,
DOI : 10.1016/j.ijpara.2003.09.011
Antioxidant defense in Plasmodium falciparum--data mining of the transcriptome, Malaria Journal, vol.3, issue.1, p.23, 2004. ,
DOI : 10.1186/1475-2875-3-23
Protein disulfide isomerase: The multifunctional redox chaperone of the endoplasmic reticulum, Seminars in Cell & Developmental Biology, vol.10, issue.5, pp.481-493, 1999. ,
DOI : 10.1006/scdb.1999.0319
The Putative Glutathione Peroxidase Gene of Plasmodium falciparum Codes for a Thioredoxin Peroxidase, Journal of Biological Chemistry, vol.276, issue.10 ,
DOI : 10.1074/jbc.M008631200
Pgh1 modulates sensitivity and resistance to multiple antimalarials in Plasmodium falciparum, Nature, issue.6772, pp.403906-909, 2000. ,
Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin, The Journal of Infectious Diseases, vol.194, issue.4, pp.528-535, 2006. ,
DOI : 10.1086/507115
URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978021
Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum, The EMBO Journal, vol.3, issue.13, pp.253000-3011, 2006. ,
DOI : 10.1073/pnas.82.9.2784
The pfmdr1 gene is associated with a multidrug-resistant phenotype in Plasmodium falciparum from the western border of Thailand, Antimicrob Agents Chemother, issue.12, pp.432943-2949, 1999. ,
Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number, The Lancet, vol.364, issue.9432, pp.364438-447, 2004. ,
DOI : 10.1016/S0140-6736(04)16767-6
Contribution of the pfmdr1 gene to antimalarial drug-resistance, Acta Tropica, vol.94, issue.3, pp.181-190, 2005. ,
DOI : 10.1016/j.actatropica.2005.04.008
Make It or Take It: Fatty Acid Metabolism of Apicomplexan Parasites, Eukaryotic Cell, vol.6, issue.10, pp.1727-1735, 2007. ,
DOI : 10.1128/EC.00255-07
Duplication, gene conversion, and genetic diversity in the species-specific acyl-CoA synthetase gene family of Plasmodium falciparum, Molecular and Biochemical Parasitology, vol.150, issue.1, pp.10-24, 2006. ,
DOI : 10.1016/j.molbiopara.2006.06.004
The C-terminal domain of the Plasmodium falciparum acyl-CoA synthetases PfACS1 and PfACS3 functions as ligand for ankyrin, Molecular and Biochemical Parasitology, vol.129, issue.2, pp.191-198, 2003. ,
DOI : 10.1016/S0166-6851(03)00123-3
Membrane transporters in the relict plastid of malaria parasites, Proceedings of the National Academy of Sciences, vol.103, issue.25, pp.9572-9577, 2006. ,
DOI : 10.1073/pnas.0602293103
Metabolic maps and functions of the Plasmodium falciparum apicoplast, Nature Reviews Microbiology, vol.16, issue.3, pp.203-216, 2004. ,
DOI : 10.1093/nar/gkg081
Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparum, Nature, vol.6, issue.7131, pp.44688-91, 2007. ,
DOI : 10.1038/nature05572
The role of the mitochondrial permeability transition in cell death, Mitochondrion, vol.6, issue.5, pp.225-234, 2006. ,
DOI : 10.1016/j.mito.2006.07.006
Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote, BMC Genomics, vol.5, issue.1, p.79, 2004. ,
DOI : 10.1186/1471-2164-5-79
URL : https://hal.archives-ouvertes.fr/inserm-00103327
Transport processes in Plasmodium falciparum-infected erythrocytes: potential as new drug targets, International Journal for Parasitology, vol.32, issue.13, pp.321567-1573, 2002. ,
DOI : 10.1016/S0020-7519(02)00185-6
A new Apicomplexa-specific protein kinase family: multiple members in Plasmodium falciparum, all with an export signature, BMC Genomics, vol.6, issue.1, p.30, 2005. ,
DOI : 10.1186/1471-2164-6-30
is differentially transcribed and secreted to various cellular compartments of the host cell, Molecular Microbiology, vol.207, issue.2, pp.391-403, 2007. ,
DOI : 10.1111/j.1365-2958.2006.05521.x
Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle, Genome Res, issue.11, pp.142308-2318, 2004. ,
A Comprehensive Survey of the Plasmodium Life Cycle by Genomic, Transcriptomic, and Proteomic Analyses, Science, vol.307, issue.5706, pp.30782-86, 2005. ,
DOI : 10.1126/science.1103717
Variant antigen gene expression in malaria, Cellular Microbiology, vol.439, issue.9, pp.1371-1381, 2006. ,
DOI : 10.1016/S0166-6851(03)00004-5
Developmentally regulated expression of pfs16, a marker for sexual differentiation of the human malaria parasite Plasmodium falciparum, Molecular and Biochemical Parasitology, vol.89, issue.2, pp.235-244, 1997. ,
DOI : 10.1016/S0166-6851(97)00123-0
Whole-genome analysis of mRNA decay in Plasmodium falciparum reveals a global lengthening of mRNA half-life during the intra-erythrocytic development cycle, Genome Biology, vol.8, issue.7, p.134, 2007. ,
DOI : 10.1186/gb-2007-8-7-r134
Sticky fingers: zinc-fingers as protein-recognition motifs, Trends in Biochemical Sciences, vol.32, issue.2, pp.63-70, 2007. ,
DOI : 10.1016/j.tibs.2006.12.007
Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs, Angew Chem Int Ed Engl, issue.33, pp.466278-6283, 2007. ,
Artemisinins target the SERCA of Plasmodium falciparum, Nature, vol.424, issue.6951, pp.424957-961, 2003. ,
DOI : 10.1038/nature01813
In Vitro Monitoring of Plasmodium falciparum Drug Resistance in French Guiana: a Synopsis of Continuous Assessment from 1994 to 2005, Antimicrobial Agents and Chemotherapy, vol.52, issue.1, pp.288-298, 1994. ,
DOI : 10.1128/AAC.00263-07
URL : https://hal.archives-ouvertes.fr/pasteur-00590986
Artemisinin Induces Calcium-Dependent Protein Secretion in the Protozoan Parasite Toxoplasma gondii, Eukaryotic Cell, vol.6, issue.11, pp.2147-2156, 2007. ,
DOI : 10.1128/EC.00262-07
Morphologic effects of artemisinin in Plasmodium falciparum, Am J Trop Med Hyg, vol.49, issue.4, pp.485-491, 1993. ,
Artemisinin and a Series of Novel Endoperoxide Antimalarials Exert Early Effects on Digestive Vacuole Morphology, Antimicrobial Agents and Chemotherapy, vol.52, issue.1, pp.98-109, 2008. ,
DOI : 10.1128/AAC.00609-07
Artemisinin and its derivatives are transported by a vacuolar-network of Plasmodium falciparum and their anti-malarial activities are additive with toxic sphingolipid analogues that block the network, Molecular and Biochemical Parasitology, vol.101, issue.1-2, pp.71-79, 1999. ,
DOI : 10.1016/S0166-6851(99)00056-0
Protein export from Plasmodium parasites, Cellular Microbiology, vol.11, issue.3, pp.573-582, 2007. ,
DOI : 10.1016/S0092-8674(02)01250-3
Towards a proteomic definition of CoArtem action inPlasmodium falciparum malaria, PROTEOMICS, vol.70, issue.7, pp.1849-1858, 2005. ,
DOI : 10.1002/pmic.200401076
Plasmodium falciparum Erythrocyte Membrane Protein 3 (PfEMP3) Destabilizes Erythrocyte Membrane Skeleton, Journal of Biological Chemistry, vol.282, issue.37, pp.26754-26758, 2007. ,
DOI : 10.1074/jbc.M701612200
Trafficking determinants for PfEMP3 export and assembly under the Plasmodium falciparum-infected red blood cell membrane ,
Exported Proteins Required for Virulence and Rigidity of Plasmodium falciparum-Infected Human Erythrocytes, Cell, vol.134, issue.1, pp.48-61, 2008. ,
DOI : 10.1016/j.cell.2008.04.051
Adhesion Molecules and Other Secreted Host???Interaction Determinants in Apicomplexa: Insights from Comparative Genomics, Int Rev Cytol, vol.262, pp.1-74, 2007. ,
DOI : 10.1016/S0074-7696(07)62001-4
In vivo and in vitro derived Palo Alto lines of Plasmodium falciparum are genetically unrelated, Molecular and Biochemical Parasitology, vol.47, issue.2, pp.167-178, 1991. ,
DOI : 10.1016/0166-6851(91)90176-7
Transcriptome analysis of antigenic variation in Plasmodium falciparum--var silencing is not dependent on antisense RNA, Genome Biology, vol.6, issue.11, p.93, 2005. ,
DOI : 10.1186/gb-2005-6-11-r93
R: A language and environment for statistical computing ,
Bioconductor: open software development for computational biology and bioinformatics, Genome Biology, vol.5, issue.10, p.80, 2004. ,
DOI : 10.1186/gb-2004-5-10-r80
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments, Statistical Applications in Genetics and Molecular Biology, vol.3, issue.1, p.3, 2004. ,
DOI : 10.2202/1544-6115.1027
limma: Linear Models for Microarray Data, In Bioinformatics and Computational Biology Solutions using R and Bioconductor Edited, pp.397-420, 2005. ,
DOI : 10.1007/0-387-29362-0_23
URL : http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.182.2271
Normalization for two-color cDNA microarray data. Science and Statistics: A Festschrift for Terry Speed, IMS Lecture Notes -Monograph Series, pp.403-418, 2003. ,
DOI : 10.1214/lnms/1215091155
URL : http://projecteuclid.org/download/pdf_1/euclid.lnms/1215091155