Leishmaniasis Worldwide and Global Estimates of Its Incidence, PLoS ONE, vol.83, issue.30, p.35671, 2012. ,
DOI : 10.1371/journal.pone.0035671.s101
Leishmaniasis and poverty, Trends in Parasitology, vol.22, issue.12, pp.552-557, 2006. ,
DOI : 10.1016/j.pt.2006.09.004
Leishmaniasis: current situation and new perspectives, Comparative Immunology, Microbiology and Infectious Diseases, vol.27, issue.5, pp.305-318, 2004. ,
DOI : 10.1016/j.cimid.2004.03.004
Advances in leishmaniasis, The Lancet, vol.366, issue.9496, pp.1561-1577, 2005. ,
DOI : 10.1016/S0140-6736(05)67629-5
Antimony Toxicity, International Journal of Environmental Research and Public Health, vol.7, issue.12, pp.4267-4277, 2010. ,
DOI : 10.3390/ijerph7124267
URL : http://doi.org/10.3390/ijerph7124267
Electrocardiographic and biochemical adverse effects of sodium stibogluconate during treatment of cutaneous and mucosal leishmaniasis among returned travellers, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.100, issue.3, pp.264-269, 2006. ,
DOI : 10.1016/j.trstmh.2005.03.012
High frequency of serious side effects from meglumine antimoniate given without an upper limit dose for the treatment of visceral leishmaniasis in human immunodeficiency virus type-1-infected patients, Am J Trop Med Hyg, vol.61, pp.766-769, 1999. ,
Drug regimens for visceral leishmaniasis in Mediterranean countries, Tropical Medicine & International Health, vol.15, issue.Suppl. 1, pp.1272-1276, 2008. ,
DOI : 10.1111/j.1365-3156.2008.02144.x
Comparison of three treatment regimens with liposomal amphotericin B (AmBisome??) for visceral leishmaniasis in India: a randomized dose-finding study, Transactions of the Royal Society of Tropical Medicine and Hygiene, vol.90, issue.3, pp.319-322, 1996. ,
DOI : 10.1016/S0035-9203(96)90271-0
Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen, PLoS Neglected Tropical Diseases, vol.8, issue.11, p.540, 2009. ,
DOI : 10.1371/journal.pntd.0000540.s003
Antileishmanial High-Throughput Drug Screening Reveals Drug Candidates with New Scaffolds, PLoS Neglected Tropical Diseases, vol.73, issue.5, p.675, 2010. ,
DOI : 10.1371/journal.pntd.0000675.s002
URL : https://hal.archives-ouvertes.fr/pasteur-00696809
Life in vacuoles ??? nutrient acquisition by Leishmania amastigotes, International Journal for Parasitology, vol.31, issue.12, pp.1311-1320, 2001. ,
DOI : 10.1016/S0020-7519(01)00259-4
Post-translational modification of cellular proteins duringLeishmania donovani differentiation, PROTEOMICS, vol.281, issue.9, pp.1843-1850, 2008. ,
DOI : 10.1002/pmic.200701043
Retooling Leishmania metabolism: from sand fly gut to human macrophage, The FASEB Journal, vol.22, issue.2, pp.590-602, 2008. ,
DOI : 10.1096/fj.07-9254com
Analysis of the Leishmania donovani transcriptome reveals an ordered progression of transient and permanent changes in gene expression during differentiation, Molecular and Biochemical Parasitology, vol.152, issue.1, pp.53-65, 2007. ,
DOI : 10.1016/j.molbiopara.2006.11.011
: drug sensititvitles of promastigotes and transforming amastigotes, Journal of Antimicrobial Chemotherapy, vol.11, issue.2, pp.151-162, 1983. ,
DOI : 10.1093/jac/11.2.151
A Screen against Leishmania Intracellular Amastigotes: Comparison to a Promastigote Screen and Identification of a Host Cell-Specific Hit, PLoS Neglected Tropical Diseases, vol.129, issue.7, p.1253, 2011. ,
DOI : 10.1371/journal.pntd.0001253.t001
In Vitro Susceptibilities of Leishmania donovani Promastigote and Amastigote Stages to Antileishmanial Reference Drugs: Practical Relevance of Stage-Specific Differences, Antimicrobial Agents and Chemotherapy, vol.53, issue.9, pp.3855-3859, 2009. ,
DOI : 10.1128/AAC.00548-09
Treatment of Experimental Leishmaniasis with the Immunomodulators Imiquimod and S???28463: Efficacy and Mode of Action, The Journal of Infectious Diseases, vol.179, issue.6, pp.1485-1494, 1999. ,
DOI : 10.1086/314782
Modulation of Gene Expression in Human Macrophages Treated with the Anti-Leishmania Pentavalent Antimonial Drug Sodium Stibogluconate, Antimicrobial Agents and Chemotherapy, vol.52, issue.2, pp.526-533, 2008. ,
DOI : 10.1128/AAC.01183-07
Leishmania Repression of Host Translation through mTOR Cleavage Is Required for Parasite Survival and Infection, Cell Host & Microbe, vol.9, issue.4, pp.331-341, 2011. ,
DOI : 10.1016/j.chom.2011.03.008
Innate Killing of Leishmania donovani by Macrophages of the Splenic Marginal Zone Requires IRF-7, PLoS Pathogens, vol.39, issue.8, p.1000813, 2010. ,
DOI : 10.1371/journal.ppat.1000813.s014
New antileishmanial candidates and lead compounds, Current Opinion in Chemical Biology, vol.14, issue.4, pp.447-455, 2010. ,
DOI : 10.1016/j.cbpa.2010.03.023
Sorting of Leishmania-bearing dendritic cells reveals subtle parasite-induced modulation of host-cell gene expression, Microbes and Infection, vol.12, issue.1, pp.46-54, 2010. ,
DOI : 10.1016/j.micinf.2009.09.014
Destruction of Leishmania mexicana amazonensis amastigotes within macrophages by lysosomotropic amino acid esters, Journal of Experimental Medicine, vol.163, issue.3, pp.520-535, 1986. ,
DOI : 10.1084/jem.163.3.520
Leishmania mexicana: Temperature sensitivity of isolated amastigotes and of amastigotes infecting macrophages in culture, Experimental Parasitology, vol.56, issue.3, pp.289-297, 1983. ,
DOI : 10.1016/0014-4894(83)90074-7
Leishmania DNA is rapidly degraded following parasite death: an analysis by microscopy and real-time PCR, Microbes and Infection, vol.9, issue.11, pp.1307-1315, 2007. ,
DOI : 10.1016/j.micinf.2007.06.005
URL : https://hal.archives-ouvertes.fr/pasteur-00181350
Transcriptional signatures of BALB/c mouse macrophages housing multiplying Leishmania amazonensis amastigotes, BMC Genomics, vol.10, issue.1, p.119, 2009. ,
DOI : 10.1186/1471-2164-10-119
URL : https://hal.archives-ouvertes.fr/pasteur-00376739
Statistical methods for analysis of high-throughput RNA interference screens, Nature Methods, vol.5, issue.8, pp.569-575, 2009. ,
DOI : 10.1093/nar/gkn435
Illustration of SSMD, z Score, SSMD*, z* Score, and t Statistic for Hit Selection in RNAi High-Throughput Screens, Journal of Biomolecular Screening, vol.16, issue.7, pp.775-785, 2011. ,
DOI : 10.1177/1087057111405851
A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays, Journal of Biomolecular Screening, vol.4, issue.2, pp.67-73, 1999. ,
DOI : 10.1177/108705719900400206
Novel Analytic Criteria and Effective Plate Designs for Quality Control in Genome-Scale RNAi Screens, Journal of Biomolecular Screening, vol.21, issue.5, pp.363-377, 2008. ,
DOI : 10.1177/1087057108317062
Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation, Cellular Microbiology, vol.48, issue.7, pp.978-991, 2011. ,
DOI : 10.1111/j.1462-5822.2011.01593.x
URL : https://hal.archives-ouvertes.fr/pasteur-01433560
Effect of differentiating agents (all-trans retinoic acid and phorbol 12-myristate 13-acetate) on drug sensitivity of HL60 and NB4 cells in vitro., Folia Histochemica et Cytobiologica, vol.46, issue.3, pp.323-330, 2008. ,
DOI : 10.2478/v10042-008-0080-x
Comparison of retinoic acid and phorbol myristate acetate as inducers of monocytic differentiation, International Journal of Cancer, vol.12, issue.1, pp.98-103, 1994. ,
DOI : 10.1002/ijc.2910570118
Dendritic cells as host cells for the promastigote and amastigote stages of Leishmania amazonensis: the role of opsonins in parasite uptake and dendritic cell maturation, Journal of Cell Science, vol.117, issue.2, pp.315-325, 2004. ,
DOI : 10.1242/jcs.00860
The biogenesis and properties of the parasitophorous vacuoles that harbour Leishmania in murine macrophages, Trends in Microbiology, vol.6, issue.10, pp.392-401, 1998. ,
DOI : 10.1016/S0966-842X(98)01324-9
Parasitophorous vacuoles of Leishmania amazonensis-infected macrophages maintain an acidic pH, Infect Immun, vol.58, pp.779-787, 1990. ,
Synthesis and biological evaluation of substituted quinolines: potential treatment of protozoal and retroviral co-infections, Bioorganic & Medicinal Chemistry, vol.11, issue.23, pp.5013-5023, 2003. ,
DOI : 10.1016/j.bmc.2003.09.007
-butyl-paullones: A New Antileishmanial Chemotype, Journal of Medicinal Chemistry, vol.51, issue.3, pp.659-665, 2008. ,
DOI : 10.1021/jm7012166
A new Heck reaction modification using ketone Mannich bases as enone precursors: Parallel synthesis of anti-leishmanial chalcones, Bioorganic & Medicinal Chemistry Letters, vol.18, issue.6, pp.1985-1989, 2008. ,
DOI : 10.1016/j.bmcl.2008.01.112
Leishmania infantumPromastigotes: Flow Cytometry as a Possible Tool for Assessing the Effects of Drugs on Cellular Functions, Experimental Parasitology, vol.87, issue.1, pp.1-7, 1997. ,
DOI : 10.1006/expr.1997.4182
Activity of imidazoles against Leishmania tropica in human macrophage cultures, Am J Tropl Med Hyg, vol.30, pp.566-569, 1981. ,
Topical treatment with imidazole for cutaneous leishmaniasis, Isr J Med Sci, vol.21, pp.163-164, 1985. ,
A randomized, double-blind, clinical trial of topical clotrimazole versus miconazole for treatment of cutaneous leishmaniasis in the eastern province of Saudi Arabia, Am J Trop Med Hyg, vol.52, pp.166-168, 1995. ,
Cutaneous leishmaniasis: Failure of topical treatment with imidazole derivatives in laboratory animals and man, Archives of Dermatological Research, vol.275, issue.2, pp.133-134, 1984. ,
DOI : 10.1007/BF00511073
An Image-Based High-Content Screening Assay for Compounds Targeting Intracellular Leishmania donovani Amastigotes in Human Macrophages, PLoS Neglected Tropical Diseases, vol.5, issue.6, p.1671, 2012. ,
DOI : 10.1371/journal.pntd.0001671.s007
URL : https://hal.archives-ouvertes.fr/pasteur-00850256
Chemical genetics of Plasmodium falciparum, Nature, vol.12, issue.7296, pp.311-315, 2010. ,
DOI : 10.1038/nature09099
Colorimetric assay for screening compounds against Leishmania amastigotes grown in macrophages, Am J Trop Med Hyg, vol.72, pp.600-605, 2005. ,
Collaborative actions in anti-trypanosomatid chemotherapy with partners from disease endemic areas, Trends in Parasitology, vol.26, issue.8, pp.395-403, 2010. ,
DOI : 10.1016/j.pt.2010.04.012
URL : https://hal.archives-ouvertes.fr/pasteur-01433565