Genetic Diversity and Phylogeny of Aedes aegypti, the Main Arbovirus Vector in the Pacific

Elodie Calvez (1) , Laurent Guillaumot (1) , Laurent Millet (2) , Jérôme Marie (3) , Hervé Bossin (3) , Vineshwaran Rama (4) , Akata Faamoe (5) , Sosiasi Kilama (1) , Magali Teurlai (1) , Françoise Mathieu-Daudé (6) , Myrielle Dupont-Rouzeyrol (1)

1 Institut Pasteur de Nouvelle-Calédonie
2 IRD [Nouvelle-Calédonie] - Institut de Recherche pour le Développement
3 ILM - Institut Louis Malardé [Papeete]
4 Ministère de la santé (Fidji)
5 Ministère de la santé (Tonga)
6 MIVEGEC-VCG - Vector Control Group

Aedes aegypti is the major arbovirus vector in the Pacific region. The spread of this mosquito in the different islands seems to be linked to human activities at the beginning of the twentieth century. Since 2010, occurrence of arbovirus outbreaks increased in this region, with the co-circulation of dengue, chikungunya and Zika viruses. The lack of vaccines and treatments for these pathogens led the health authorities to implement vector control measures. In this study, we present the genetic structure and the phylogenetic data obtained from the analysis of 270 Ae. aegypti collected in the Pacific region. The infestation of the islands seems to have American and Asian origins. The genetic structure of the vector populations indicates a differentiation of the mosquitoes between the western, central and eastern Pacific island countries and the specific island isolation context. This differentiation could be related to the different environmental conditions in each island country.

Domaines: Sciences du Vivant [q-bio]

Elodie Calvez, Laurent Guillaumot, Laurent Millet, Jérôme Marie, Hervé Bossin, et al.. Genetic Diversity and Phylogeny of Aedes aegypti, the Main Arbovirus Vector in the Pacific. PLoS Neglected Tropical Diseases, 2016, ⟨10.1371/journal.pntd.0004374⟩. ⟨pasteur-01267472⟩