Toward the Discovery of Vaccine Adjuvants: Coupling In Silico Screening and In Vitro Analysis of Antagonist Binding to Human and Mouse CCR4 Receptors

Matthew Davies (1) , Jagadeesh Bayry (2, 3, 4, 5) , Elma Tchilian , Janakiraman Vani (6) , Melkote Shaila , Emily Forbes , Simon Draper , Peter Beverley , David Tough , Darren Flower

1 Centre for Digital Music
2 CRC - Centre de Recherche des Cordeliers
3 UPMC - Université Pierre et Marie Curie - Paris 6 - UFR de Médecine Pierre et Marie Curie
4 USPC - Université Sorbonne Paris Cité
5 INSERM - Institut National de la Santé et de la Recherche Médicale
6 CRC (UMR_S_1138 / U1138) - Centre de Recherche des Cordeliers

Domaines: Immunité innée; Allergologie

Matthew Davies, Jagadeesh Bayry, Elma Tchilian, Janakiraman Vani, Melkote Shaila, et al.. Toward the Discovery of Vaccine Adjuvants: Coupling In Silico Screening and In Vitro Analysis of Antagonist Binding to Human and Mouse CCR4 Receptors. PLoS ONE, 2009, 4 (11), pp.e8084. ⟨10.1371/journal.pone.0008084⟩. ⟨inserm-02455591⟩