Early estimates of 2014/15 seasonal influenza vaccine effectiveness in preventing influenza-like illness in general practice using the screening method in France

Cécile Souty (1) , Thierry Blanchon (1) , Isabelle Bonmarin (2) , Daniel Lévy-Bruhl (2) , Sylvie Behillil (3, 4) , Vincent Enouf (3, 4) , Martine Valette (3, 5) , Maude Bouscambert (3, 5) , Clément Turbelin (1) , Lisandru Capai (6, 1) , Victoire Roussel (1) , Thomas Hanslik (7, 1, 8) , Alessandra Falchi (6)

1 iPLESP - Institut Pierre Louis d'Epidémiologie et de Santé Publique
2 Département des maladies infectieuses
3 CNR - Centre National de Référence des virus influenzae (Grippe)
4 Virologie Structurale - Structural Virology
5 Centre National de Référence Virus Influenza (Région Sud)
6 EA Bioscope Corse Méditerranée : Dynamique des infections virales en milieu insulaire
7 UVSQ Santé - Université de Versailles Saint-Quentin-en-Yvelines - UFR Sciences de la santé Simone Veil
8 Service de Médecine Interne

The ongoing influenza epidemic is characterized by intense activity with most influenza infections due to the A(H3N2) viruses. Using the screening method, mid-season vaccine effectiveness (VE) in preventing influenza-like illness in primary care was estimated to 32% (95% CI; 23 to 40) among risk groups and was 11% (95% CI; -4 to 23) among the elderly (≥65 years). The VE in ≥65 y was the lowest estimate regarding the 4 previous seasonal influenza epidemics.

Mots clés: primary care; vaccine effectiveness; France; influenza-like illness influenza

Domaines: Santé publique et épidémiologie; Maladies infectieuses

Cécile Souty, Thierry Blanchon, Isabelle Bonmarin, Daniel Lévy-Bruhl, Sylvie Behillil, et al.. Early estimates of 2014/15 seasonal influenza vaccine effectiveness in preventing influenza-like illness in general practice using the screening method in France. Human Vaccines & Immunotherapeutics, 2013, 20 (2 Suppl), pp.88-93. ⟨10.1080/21645515.2015.1046661⟩. ⟨inserm-01199293⟩