3-D Modeling of the Thermal Coagulation Necrosis Induced by an Interstitial Ultrasonic Transducer.

Carole Garnier (1) , Cyril Lafon (2) , Jean-Louis Dillenseger (1)

1 LTSI - Laboratoire Traitement du Signal et de l'Image
2 Applications des ultrasons à la thérapie

This letter describes a temperature-varying attenuation approach for preoperative planning of high intensity ultrasound interstitial targeted therapy. Such approach is mainly aimed at the treatment of primary liver cancer for which a precise lesion control must be achieved. It is shown through simulation that the shape and size of the resulting necrotic volume is significantly different from the one obtained when this tissue property is considered constant in time.

Mots clés: Medical imaging; modeling; modelisation; high intensity ultrasound therapy; hyperthermia; interstitial therapy; planning; simulation; tissue properties

Domaines: Ingénierie biomédicale

Carole Garnier, Cyril Lafon, Jean-Louis Dillenseger. 3-D Modeling of the Thermal Coagulation Necrosis Induced by an Interstitial Ultrasonic Transducer.. IEEE Transactions on Biomedical Engineering, 2008, 55 (2), pp.833-837. ⟨10.1109/TBME.2007.914543⟩. ⟨inserm-00255894⟩