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Reconstruction of Coronary Arteries from a Single Rotational X-Ray Projection Sequence

Christophe Blondel 1 Grégoire Malandain 2, * Régis Vaillant 3, 4 Nicholas Ayache 2, *
* Corresponding author
1 CHIR - Surgery, Informatics and Robotics
CRISAM - Inria Sophia Antipolis - Méditerranée
2 ASCLEPIOS - Analysis and Simulation of Biomedical Images
CRISAM - Inria Sophia Antipolis - Méditerranée
4 ROBOTVIS - Computer Vision and Robotics
CRISAM - Inria Sophia Antipolis - Méditerranée
Abstract : Cardiovascular diseases remain the primary cause of death in developed countries. In most cases, exploration of possibly underlying coronary artery pathologies is performed using X-ray coronary angiography. Current clinical routine in coronary angiography is directly conducted in 2-D projection images from several static viewing angles. However, for diagnosis and treatment purposes, coronary artery reconstruction is highly suitable. The purpose of this study is to provide physicians with a 3-D model of coronary arteries, e.g. for absolute three-dimensional measures for lesion assessment, instead of direct projective measures deduced from the images, which are highly dependent on the viewing angle. In this article, we propose a novel method to reconstruct coronary arteries from one single rotational X-ray projection sequence. As a side result, we also obtain an estimation of the coronary artery motion. Our method consists of 3 main consecutive steps: (1) 3-D reconstruction of coronary artery centerlines, including respiratory motion compensation, (2) coronary artery 4-D motion computation, and (3) 3-D tomographic reconstruction of coronary arteries, involving compensation for respiratory and cardiac motions. We present some experiments on clinical datasets, and the feasibility of a true 3-D Quantitative Coronary Analysis is demonstrated.
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Christophe Blondel, Grégoire Malandain, Régis Vaillant, Nicholas Ayache. Reconstruction of Coronary Arteries from a Single Rotational X-Ray Projection Sequence. IEEE Transactions on Medical Imaging, Institute of Electrical and Electronics Engineers, 2006, 25 (5), pp.653--663. ⟨10.1109/TMI.2006.873224⟩. ⟨inria-00614993⟩

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