S. Frank-alber, L. M. Dokudovskaya, W. Veenhoff, J. Zhang, D. Kipper et al., The molecular architecture of the nuclear pore complex, Nature, issue.7170, pp.450695-701, 2007.

S. Frank-alber, L. M. Dokudovskaya, W. Veenhoff, J. Zhang, D. Kipper et al., Determining the architectures of macromolecular assemblies, Nature, issue.7170, pp.450683-694, 2007.

F. Alber, D. Förster, M. Korkin, A. Topf, and . Sali, Integrating Diverse Data for Structure Determination of Macromolecular Assemblies, Annual Review of Biochemistry, vol.77, issue.1, pp.11-12, 2008.
DOI : 10.1146/annurev.biochem.77.060407.135530

G. Stephen, N. C. Brohawn, E. D. Leksa, K. R. Spear, T. U. Rajashankar et al., Structural evidence for common ancestry of the nuclear pore complex and vesicle coats, Science, vol.322, pp.1369-1373, 2008.

G. Stephen, T. U. Brohawn, and . Schwartz, Molecular architecture of the Nup84?Nup145C? Sec13 edge element in the nuclear pore complex lattice, Nature Structural & Molecular Biology, pp.1173-1178, 2009.

[. Cazals and D. Cohen-steiner, Reconstructing 3d compact sets To appear; available from ftp, Computational Geometry Theory and Applications, 2011.

[. Cazals and T. Dreyfus, Multi-scale geometric modeling of ambiguous shapes with toleranced balls and compoundly weighted ?-shapes, Symposium on Geometry Processing, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00796078

[. Cazals, K. Harshad, and S. Loriot, Computing the volume of a union of balls, ACM Transactions on Mathematical Software, vol.38, issue.1, 2011.
DOI : 10.1145/2049662.2049665

URL : https://hal.archives-ouvertes.fr/hal-00849809

[. Cazals and C. Karande, An algorithm for reporting maximal <mml:math altimg="si1.gif" overflow="scroll" xmlns:xocs="http://www.elsevier.com/xml/xocs/dtd" xmlns:xs="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns="http://www.elsevier.com/xml/ja/dtd" xmlns:ja="http://www.elsevier.com/xml/ja/dtd" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:tb="http://www.elsevier.com/xml/common/table/dtd" xmlns:sb="http://www.elsevier.com/xml/common/struct-bib/dtd" xmlns:ce="http://www.elsevier.com/xml/common/dtd" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:cals="http://www.elsevier.com/xml/common/cals/dtd"><mml:mi>c</mml:mi></mml:math>-cliques, Theoretical Computer Science, vol.349, issue.3, pp.484-490, 2005.
DOI : 10.1016/j.tcs.2005.09.038

D. Cohen-steiner, H. Edelsbrunner, and J. Harer, Stability of persistence diagrams, ACM Symp. Comp. Geometry, 2005.

. W. Dms-+-08-]-erik, Y. Debler, H. Ma, K. Seo, T. R. Hsia et al., A fence-like coat for the nuclear pore membrane, Molecular Cell, vol.32, pp.815-826, 2008.

H. Edelsbrunner, Weighted alpha shapes, Dept. Comput. Sci., Univ. Illinois, 1992.

[. Grandi, V. Doye, and E. C. Hurt, Purification of NSP1 reveals complex formation with'GLFG'nucleoporins and a novel nuclear pore protein NIC96, The EMBO Journal, vol.12, issue.8, p.3061, 1993.

J. Giesen and M. John, The flow complex: A data structure for geometric modeling, ACM SODA, 2003.
DOI : 10.1016/j.comgeo.2007.01.002

[. Harpaz, M. Gerstein, and C. Chothia, Volume changes on protein folding, Structure, vol.2, issue.7, pp.641-649, 1994.
DOI : 10.1016/S0969-2126(00)00065-4

P. Kuo-chiang-hsia, G. Stavropoulos, A. Blobel, and . Hoelz, Architecture of a Coat for the Nuclear Pore Membrane, Cell, vol.131, issue.7, pp.1313-1326, 2007.
DOI : 10.1016/j.cell.2007.11.038

S. Jeudy and T. U. Schwartz, Crystal Structure of Nucleoporin Nic96 Reveals a Novel, Intricate Helical Domain Architecture, Journal of Biological Chemistry, vol.282, issue.48, pp.34904-34912, 2007.
DOI : 10.1074/jbc.M705479200

M. Kampmann and G. Blobel, Three-dimensional structure and flexibility of a membrane-coating module of the nuclear pore complex, Nature Structural & Molecular Biology, vol.6, issue.7, pp.782-788, 2009.
DOI : 10.1006/jsbi.1998.4080

I. Koch, Enumerating all connected maximal common subgraphs in two graphs, Theoretical Computer Science, vol.250, issue.1-2, pp.1-30, 2001.
DOI : 10.1016/S0304-3975(00)00286-3

N. C. Leksa, S. G. Brohawn, and T. U. Schwartz, The Structure of the Scaffold Nucleoporin Nup120 Reveals a New and Unexpected Domain Architecture, Structure, vol.17, issue.8, pp.1082-1091, 2009.
DOI : 10.1016/j.str.2009.06.003

V. Nagy, K. Hsia, E. W. Debler, M. Kampmann, A. M. Davenport et al., Structure of a trimeric nucleoporin complex reveals alternate oligomerization states, Proceedings of the National Academy of Sciences, p.17693, 2009.
DOI : 10.1073/pnas.0909373106

A. Okabe, B. Boots, K. Sugihara, and S. N. Chiu, Spatial Tessellations: Concepts and Applications of Voronoi Diagrams, 2000.

L. Nikolaus, M. Schlaich, A. Haner, U. Lustig, E. C. Aebi et al., In vitro reconstitution of a heterotrimeric nucleoporin complex consisting of recombinant Nsp1p, Nup49p, and Nup57p, Molecular biology of the cell, vol.8, issue.1, pp.33-46, 1997.

H. Seo, Y. Ma, E. W. Debler, D. Wacker, S. Kutik et al., Structural and functional analysis of nup133 domains reveals modular building blocks of the nuclear pore complex, J. Cell Biol, vol.167, pp.591-597, 2004.

H. Seo, Y. Ma, E. W. Debler, D. Wacker, S. Kutik et al., Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex, Proceedings of the National Academy of Sciences, vol.106, issue.34, pp.14281-14286, 2009.
DOI : 10.1073/pnas.0907453106

P. Stelter, D. Flemming, R. Kunze, E. Hurt, and I. R. Vetter, Structural basis of the nic96 subcomplex organization in the nuclear pore channel, Molecular cell, vol.29, issue.1, pp.46-55, 2008.

R. R. James, T. U. Whittle, and . Schwartz, Architectural nucleoporins nup157/170 and nup133 are structurally related and descend from a second ancestral element, J. Biol. Chem, vol.284, pp.28442-28452, 2009.

C. Results and .. Analysis, 28 7.4.1 Over and Under-represented pairs in the toleranced model On k-significant contacts, p.32

I. Unité-de-recherche and . Lorraine, Technopôle de Nancy-Brabois -Campus scientifique 615, rue du Jardin Botanique -BP 101 -54602 Villers-lès-Nancy Cedex (France) Unité de recherche INRIA Rennes : IRISA, Campus universitaire de Beaulieu -35042 Rennes Cedex (France) Unité de recherche INRIA Rhône-Alpes : 655, avenue de l'Europe -38334 Montbonnot Saint-Ismier (France) Unité de recherche INRIA Rocquencourt, Domaine de Voluceau -Rocquencourt -BP 105 -78153 Le Chesnay Cedex

I. De-voluceau-rocquencourt, BP 105 -78153 Le Chesnay Cedex (France) http://www.inria.fr ISSN, pp.249-6399