Mechanotransduction in the spotlight of mechano-sensitive channels

Marjorie Guichard (1) , Sébastien Thomine (2, 1) , Jean-Marie Frachisse (2, 1)

1 I2BC - Institut de Biologie Intégrative de la Cellule
2 MINION - Approches intégratives du Transport Ionique

The study of mechanosensitive channels (MS) in living organisms has progressed considerably over the past two decades. The understanding of their roles in mechanosensation and mechanotransduction was consecrated by the awarding of the Nobel Prize in 2021 to A. Patapoutian for his discoveries on the role of MS channels in mechanoperception in humans. In this review, we first summarize the fundamental properties of MS channels and their mode of operation. Then in a second step, we provide an update on the knowledge on the families of MS channels identified in plants and the roles and functions that have been attributed to them.

Mots clés: Mechanotransduction; Mechanosensing; Channels; Mechanosensitive channels; Tension; Force; Membrane; Plant; Arabidopsis; MSL; MCA; Piezo; OSCA; TPK; MscS.

Domaines: Botanique; Biomécanique [physics.med-ph]

Marjorie Guichard, Sébastien Thomine, Jean-Marie Frachisse. Mechanotransduction in the spotlight of mechano-sensitive channels. Current Opinion in Plant Biology, 2022, 68, pp.102252. ⟨10.1016/j.pbi.2022.102252⟩. ⟨hal-03866450⟩