Bis-nor-diterpene from Cnidoscolus quercifolius (Euphorbiaceae) induces tubulin depolymerization-mediated apoptosis in BRAFmutated melanoma cells

Raimundo Gonçalves de Oliveira-Júnior (1) , Christiane Adrielly Alves Ferraz , Ana Paula de Oliveira (1) , Edigênia Cavalcante da Cruz Araújo , Grégoire Prunier (2) , Laureen Beaugeard (3) , Hugo Groult (2) , Laurent Picot (2) , Edilson Beserra de Alencar Filho (1) , Noureddine El Aouad (4) , Larissa Araújo Rolim , Jackson Roberto Guedes da Silva Almeida

1 UNIVASF - Universidade Federal do Vale do Sao Francisco
2 LIENSs - LIttoral ENvironnement et Sociétés
3 IRBI - Institut de recherche sur la biologie de l'insecte
4 Dept Ressources Nat, Fac Polydisciplinaire Larache

Domaines: Chimie; Sciences du Vivant [q-bio]; Sciences de l'environnement; Chimie organique; Cancer; Sciences pharmaceutiques

Raimundo Gonçalves de Oliveira-Júnior, Christiane Adrielly Alves Ferraz, Ana Paula de Oliveira, Edigênia Cavalcante da Cruz Araújo, Grégoire Prunier, et al.. Bis-nor-diterpene from Cnidoscolus quercifolius (Euphorbiaceae) induces tubulin depolymerization-mediated apoptosis in BRAFmutated melanoma cells. Chemico-Biological Interactions, 2022, 355, pp.109849. ⟨10.1016/j.cbi.2022.109849⟩. ⟨hal-03842367⟩