Methods for Assessing Oocyte Quality: A Review of Literature

Yassir Lemseffer , Marie-Emilie Terret (1) , Clément Campillo (2) , Elsa Labrune (3, 4, 5)

1 CIRB - Centre interdisciplinaire de recherche en biologie
2 LAMBE - UMR 8587 - Laboratoire Analyse, Modélisation et Matériaux pour la Biologie et l'Environnement
3 HCL - Hospices Civils de Lyon
4 SBRI - Institut cellule souche et cerveau / Stem Cell and Brain Research Institute
5 UCBL - Université Claude Bernard Lyon 1

The rate of infertility continues to rise in the world for several reasons, including the age of conception and current lifestyle. We list in this paper potential non-invasive and invasive techniques to assess oocyte quality. We searched the database PubMed using the terms “oocytes AND quality AND evaluation”. In the first part, we study the morphological criteria, compartment by compartment, to then focus in a second part on more objective techniques such as genetics, molecular, apoptosis, or human follicular fluid that contain biologically active molecules. The main criteria used to assess oocyte quality are morphological; however, several other techniques have been studied in women to improve oocyte quality assessment, but most of them are invasive and not usable in routine.

Domaines: Sciences du Vivant [q-bio]

Yassir Lemseffer, Marie-Emilie Terret, Clément Campillo, Elsa Labrune. Methods for Assessing Oocyte Quality: A Review of Literature. Biomedicines, 2022, 10 (9), pp.2184. ⟨10.3390/biomedicines10092184⟩. ⟨hal-03811993⟩