Influence of geographic access and socioeconomic characteristics on breast cancer outcomes: A systematic review

Benoit Conti (1) , Audrey Bochaton (2) , Hélène Charreire (3, 4) , Hélène Bonsang-Kitzis (5) , Caroline Desprès (6) , Sandrine Baffert (7) , Charlotte Ngo (5, 6)

1 LVMT - Laboratoire Ville, Mobilité, Transport
2 LADYSS - Laboratoire Dynamiques Sociales et Recomposition des Espaces
3 EREN [CRESS - U1153 / UMR_A 1125] - Nutritional Epidemiology Research Team | Equipe de Recherche en Epidémiologie Nutritionnelle
4 LAB'URBA - LAB'URBA
5 Hôpital privé des Peupliers (Paris)
6 CRC (UMR_S_1138 / U1138) - Centre de Recherche des Cordeliers
7 CEMKA

Socioeconomic and geographical inequalities in breast cancer mortality have been widely described in European countries and the United States. To investigate the combined effects of geographic access and socioeconomic characteristics on breast cancer outcomes, a systematic review was conducted exploring the relationships between: (i) geographic access to healthcare facilities (oncology services, mammography screening), defined as travel time and/or travel distance; (ii) breast cancer-related outcomes (mammography screening, stage of cancer at diagnosis, type of treatment and rate of mortality); (iii) socioeconomic status (SES) at individuals and residential context levels. In total, n = 25 studies (29 relationships tested) were included in our systematic review. The four main results are: The statistical significance of the relationship between geographic access and breast cancer-related outcomes is heterogeneous: 15 were identified as significant and 14 as non-significant. Women with better geographic access to healthcare facilities had a statistically significant fewer mastectomy (n = 4/6) than women with poorer geographic access. The relationship with the stage of the cancer is more balanced (n = 8/17) and the relationship with cancer screening rate is not observed (n = 1/4). The type of measures of geographic access (distance, time or geographical capacity) does not seem to have any influence on the results. For example, studies which compared two different measures (travel distance and travel time) of geographic access obtained similar results. The relationship between SES characteristics and breast cancer-related outcomes is significant for several variables: at individual level, age and health insurance status; at contextual level, poverty rate and deprivation index. Of the 25 papers included in the review, the large majority (n = 24) tested the independent effect of geographic access. Only one study explored the combined effect of geographic access to breast cancer facilities and SES characteristics by developing stratified models.

Domaines: Santé publique et épidémiologie; Cancer; Economies et finances; Géographie

Benoit Conti, Audrey Bochaton, Hélène Charreire, Hélène Bonsang-Kitzis, Caroline Desprès, et al.. Influence of geographic access and socioeconomic characteristics on breast cancer outcomes: A systematic review. PLoS ONE, 2022, 17 (7), pp.e0271319. ⟨10.1371/journal.pone.0271319⟩. ⟨hal-03730234⟩