ICTV Virus Taxonomy Profile: Herpesviridae 2021

Derek Gatherer (1) , Daniel P. Depledge (2) , Carol A. Hartley (3) , Moriah L. Szpara (4) , Paola K. Vaz (3) , Mária Benkő (5) , Curtis R. Brandt (6) , Neil A. Bryant (7) , Akbar Dastjerdi (8) , Andor Doszpoly (5) , Ursula A. Gompels (9) , Naoki Inoue (10) , Keith W. Jarosinski (11) , Rajeev Kaul (12) , Vincent Lacoste (13) , Peter Norberg (14) , Francesco C. Origgi (15) , Richard J. Orton (16) , Philip E. Pellett (17) , D. Scott Schmid (18) , Stephen J. Spatz (19) , James P. Stewart (20) , Jakob Trimpert (21) , Thomas B. Waltzek (22) , Andrew J. Davison (16)

1 Lancaster University
2 NYU - New York University School of Medicine
3 University of Melbourne
4 Penn State - Pennsylvania State University
5 ELTE - Eötvös Loránd University
6 University of Wisconsin-Madison
7 CAM - University of Cambridge [UK]
8 APHA - Animal and Plant Health Agency [Addlestone, UK]
9 Royal Veterinary College [London]
10 Gifu University
11 UIUC - University of Illinois at Urbana-Champaign [Urbana]
12 University of Delhi South Campus [New Delhi]
13 Institut Pasteur du Laos
14 GU - Göteborgs Universitet = University of Gothenburg
15 UNIBE - Universität Bern / University of Bern
16 University of Glasgow
17 Wayne State University School of Medicine
18 CDC - Centers for Disease Control and Prevention [Atlanta]
19 National Poultry Research Center
20 University of Liverpool
21 Freie Universität Berlin
22 UF - University of Florida [Gainesville]

Members of the family Herpesviridae have enveloped, spherical virions with characteristic complex structures consisting of symmetrical and non-symmetrical components. The linear, double-stranded DNA genomes of 125–241 kbp contain 70–170 genes, of which 43 have been inherited from an ancestral herpesvirus. In general, herpesviruses have coevolved with and are highly adapted to their hosts, which comprise many mammalian, avian and reptilian species. Following primary infection, they are able to establish lifelong latent infection, during which there is limited viral gene expression. Severe disease is usually observed only in the foetus, the very young, the immunocompromised or following infection of an alternative host. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family Herpesviridae, which is available at ictv.global/report/herpesviridae.

Mots clés: Herpesviridae; ICTV Report; taxonomy

Domaines: Virologie; Systématique, phylogénie et taxonomie

Derek Gatherer, Daniel P. Depledge, Carol A. Hartley, Moriah L. Szpara, Paola K. Vaz, et al.. ICTV Virus Taxonomy Profile: Herpesviridae 2021. Journal of General Virology, 2021, 102 (10), pp.001673. ⟨10.1099/jgv.0.001673⟩. ⟨hal-03690917⟩