How to Define a Nanozyme

Anne Robert (1, 2) , Bernard Meunier (1, 2, 3)

1 LCC - Laboratoire de chimie de coordination
2 ERL1289 - New Antimalarial Molecules and Pharmacological Approaches
3 School of Chemical Engineering and Light Industry, Guangdong University of Technology

Over the past 15 years, many articles have considered “nanozymes” as ferromagnetic nanoparticles having an “intrinsic peroxidase-like activity” in the presence of hydrogen peroxide. However, the definition and the catalytic activity of these nanozymes have been questioned. The present Perspective reports the main criteria that are essential to classify a nanoparticle as a nanozyme. It is important to consider that not all nanoparticles able to generate hydroxyl radicals in the presence of hydrogen peroxide without catalytic activity can be registered as nanozymes.

Mots clés: Nanozymes; Nanoparticles; Catalytic activity; Turnover number

Domaines: Chimie de coordination

Anne Robert, Bernard Meunier. How to Define a Nanozyme. ACS Nano, 2022, 16 (5), pp.6956-6959. ⟨10.1021/acsnano.2c02966⟩. ⟨hal-03681945⟩