Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients

Adina Lazar (1) , Claudia Bich , Maï Panchal , Nicolas Desbenoit , Vanessa Petit , David Touboul , Luce Dauphinot , Catherine Marquer , Olivier Laprévote , Alain Brunelle , Charles Duyckaerts

1 LaMCoS - Laboratoire de Mécanique des Contacts et des Structures [Villeurbanne]

Domaines: Sciences du Vivant [q-bio]; Chimie; Sciences de l'ingénieur [physics]

Adina Lazar, Claudia Bich, Maï Panchal, Nicolas Desbenoit, Vanessa Petit, et al.. Time-of-flight secondary ion mass spectrometry (TOF-SIMS) imaging reveals cholesterol overload in the cerebral cortex of Alzheimer disease patients. Acta Neuropathologica, 2013, 125 (1), pp.133-144. ⟨10.1007/s00401-012-1041-1⟩. ⟨hal-03572637⟩