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BioRoot RCS Extracts Modulate the Early Mechanisms of Periodontal Inflammation and Regeneration

Abstract : Introduction: The balance between periapical tissue inflammation and regeneration after the removal of necrotic/infected tissues is pivotal in determining the success of endodontic treatment. This study was designed to investigate the effect of silicate-based root canal sealer BioRoot RCS (BRCS; Septodont, Saint-Maur-des-Foss es, France) on modulating the inflammatory mechanisms and early steps of regeneration initiated by human periodontal ligament (PDL) fibroblasts. Methods: Samples of BRCS and Pulp Canal Sealer (PCS; SybronEndo, Orange, CA) were incubated in culture medium to obtain material extracts. To
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https://hal.archives-ouvertes.fr/hal-03547421
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Submitted on : Friday, January 28, 2022 - 3:07:46 PM
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Charlotte Jeanneau, Thomas Giraud, Patrick Laurent, Imad About. BioRoot RCS Extracts Modulate the Early Mechanisms of Periodontal Inflammation and Regeneration. Journal of Endodontics, Elsevier, 2019, 45 (8), pp.1016-1023. ⟨10.1016/j.joen.2019.04.003⟩. ⟨hal-03547421⟩

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