Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens

Juan Sanz Garcia (1) , Marie Gaschard (2, 3) , Isabelle Navizet (1) , Mehdi Sahihi (1) , Siden Top (2, 3) , Yong Wang (2, 3, 4) , Pascal Pigeon (2, 3, 4) , Anne Vessieres (2, 3) , Michèle Salmain (3, 2) , Gerard Jaouen (2, 3, 4)

1 MSME - Laboratoire Modélisation et Simulation Multi-Echelle
2 IPCM - Institut Parisien de Chimie Moléculaire
3 CHEMBIO - Chemical Biology
4 ENSCP - Ecole Nationale Supérieure de Chimie de Paris - Chimie ParisTech-PSL

Domaines: Chimie organique; Chemo-informatique; Chimie de coordination; Chimie thérapeutique

Juan Sanz Garcia, Marie Gaschard, Isabelle Navizet, Mehdi Sahihi, Siden Top, et al.. Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens. European Journal of Inorganic Chemistry, 2022, 2022 (9), pp.e202101075. ⟨10.1002/ejic.202101075⟩. ⟨hal-03527077⟩