Is cell-free DNA in spent embryo culture medium an alternative to embryo biopsy for preimplantation genetic testing? A systematic review

Sophie Brouillet (1, 2, 3) , Guillaume Martinez (4) , Charles Coutton (4) , Samir Hamamah (2, 3)

1 BCI - Biologie du Cancer et de l'Infection
2 UMR 1203 - Développement embryonnaire précoce humain et pluripotence EmbryoPluripotency
3 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]
4 IAB - Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble)

Domaines: Sciences du Vivant [q-bio]

Sophie Brouillet, Guillaume Martinez, Charles Coutton, Samir Hamamah. Is cell-free DNA in spent embryo culture medium an alternative to embryo biopsy for preimplantation genetic testing? A systematic review. Reproductive BioMedicine Online, 2020, 40, pp.779 - 796. ⟨10.1016/j.rbmo.2020.02.002⟩. ⟨hal-03490312⟩