The Prescription of Drug Ontology 2.0 (PDRO): More Than the Sum of Its Parts
Résumé
While drugs and related products have profoundly changed the lives of people around theworld, ongoing challenges remain, including inappropriate use of a drug product. Inappropriateuses can be explained in part by ambiguous or incomplete information, for example, missing reasonsfor treatments, ambiguous information on how to take a medication, or lack of information onmedication-related events outside the health care system. In order to fully assess the situation, datafrom multiple systems (electronic medical records, pharmacy and radiology information systems,laboratory management systems, etc.) from multiple organizations (outpatient clinics, hospitals,long-term care facilities, laboratories, pharmacies, registries, governments) on a large geographicalscale is needed. Formal knowledge models like ontologies can help address such an informationintegration challenge. Existing approaches like the Observational Medical Outcomes Partnership arediscussed and contrasted with the use of ontologies and systems using them for data integration.The PRescription Drug Ontology 2.0 (PDRO 2.0) is then presented and entities that are paramount inaddressing this problematic are described. Finally, the benefits of using PDRO are discussed througha series of exemplar situation.
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