Chapter 39: Guidelines for creating a user-friendly and open-access gene expression database for comparing embryonic development and regeneration in Nematostella vectensis

Olivier Croce (1, 2) , Eric Röttinger (1, 2)

1 IRCAN - Institut de Recherche sur le Cancer et le Vieillissement
2 IFR MARRES - Institut Fédératif de Recherche - Ressources Marines

The sea anemone Nematostella vectensis has emerged as a powerful research model to understand at the gene regulatory network level, to what extend regeneration recapitulates embryonic development. Such comparison involves massive transcriptomic analysis, a routine approach for identifying differential gene expression. Here we present a workflow to build a userfriendly, mineable and open-access database providing access to the scientific community to various RNAseq datasets.

Mots clés: Database; Data mining; Open-access; RNAseq; Cnidarian; Nematostella vectensis; Regeneration; Embryonic development

Domaines: Sciences du Vivant [q-bio]

Olivier Croce, Eric Röttinger. Chapter 39: Guidelines for creating a user-friendly and open-access gene expression database for comparing embryonic development and regeneration in Nematostella vectensis. Methods in Molecular Biology - Whole Body Regeneration, In press. ⟨hal-03437921⟩