Skip to Main content Skip to Navigation
Journal articles

Mechanical properties of fused sagittal sutures in scaphocephaly

Abstract : Background: Craniosynostosis in newborns is caused by the premature closure of the cranial sutures leading to cranial vault deformity. It results in aesthetic imbalance and developmental disabilities and surgery is frequent during the first months of growth. Our study focused on scaphocephaly defined as the premature closure of the sagittal suture. We hypothesised that the effective mechanical properties of sutures were altered as compared to those of the parietal adjacent tissue considered as control. Methods: The population consisted of seven males and four females (mean age 4.9 months). Sixteen suture samples and thirty-four parietal tissue samples were harvested during corrective surgery and investigated by using three-point bending tests to obtain the structure-stiffness of specimens. An energy model was used to derive the effective Young’s modulus. A histological study complemented the experimental protocol. Findings: Fused sutures were thicker than adjacent bone and the natural curvature of sutures did not influence the static mechanical response. The stiffness of stenotic sutures was significantly higher than that of the parietal bone. The effective Young’s modulus of stenotic sutures was significantly lower than that of the parietal adjacent tissue. The parietal tissue showed a parallel bone architecture whereas the central stenotic tissue was disorganised with more vascularisation. Interpretation: The stenotic suture differed in structural and mechanical terms from the adjacent bone during calvarial growth in the first year of life. Our study emphasised the alteration of effective tissue properties in craniosynostosis. Keywords: scaphocephaly, craniosynostosis, biomechanics, mechanobiology, paediatrics, morphogenesis.
Complete list of metadata

https://hal.archives-ouvertes.fr/hal-03382268
Contributor : Open Archive Toulouse Archive Ouverte (oatao) Connect in order to contact the contributor
Submitted on : Monday, October 18, 2021 - 10:31:23 AM
Last modification on : Wednesday, October 20, 2021 - 1:43:03 AM

File

27786_Swider.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Pascal Swider, Franck Delanoé, Florian Jalbert, Sergio Boetto, Pauline Assemat, et al.. Mechanical properties of fused sagittal sutures in scaphocephaly. Clinical Biomechanics, Elsevier, 2021, 86, pp.105369. ⟨10.1016/j.clinbiomech.2021.105369⟩. ⟨hal-03382268⟩

Share

Metrics

Record views

7

Files downloads

16