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Self-representation in Kleine-Levin syndrome: a single case fMRI study

Abstract : Kleine-Levin syndrome (KLS) is characterized by recurrent episodes of hypersomnia, compulsive hyperphagia, disinhibition, hypersexuality and self modifications. To investigate the Self, we used afunctional magnetic resonance imaging paradigm evaluating Self-reference processing (SRP) and Self-reference effect (SRE) in a17-year-old male adolescent at the end of an episode. We observed enhanced activations in right hemisphere and posterior areas- associated with physical Self representations- during the SRP condition, while during the SRE condition, enhanced activations in bilateral but prevailing left frontal areas- associated with the conceptual Self. These results suggest amodified Self during aKLS episode being more physically grounded.
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Contributor : Laurent Jonchère Connect in order to contact the contributor
Submitted on : Friday, October 15, 2021 - 9:37:54 AM
Last modification on : Wednesday, March 30, 2022 - 9:24:02 AM



P Desaunay, F Dégeilh, F Guénolé, F Eustache, A Viard, et al.. Self-representation in Kleine-Levin syndrome: a single case fMRI study. Neurocase, Taylor & Francis (Routledge), 2021, pp.1-11. ⟨10.1080/13554794.2021.1974488⟩. ⟨hal-03379605⟩



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