Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling

Michael Li (1) , Hiren Patel , Armand Cognetta (2) , Trever Smith , Ivy Mallick (3) , Jean-François Cavalier (3) , Mary Previti , Stéphane Canaan (3) , Bree Aldridge (4) , Benjamin Cravatt (2) , Jessica Seeliger (5)

1 Stony Brook University, Department of Pharmacological Sciences and Immunology Stony Brook University, Stony Brook, NY 11790, USA
2 Department of Chemistry [Scripps Research Institute]
3 LISM - Laboratoire d'ingénierie des systèmes macromoléculaires
4 Department of Molecular Biology and Microbiology, Tufts University School of Medicine, and Howard Hughes Medical Institute, Boston, Massachusetts 02111
5 Stony Brook University, Department of Pharmacological Sciences and Immunology Stony Brook University, Stony Brook, NY 11790, USA

Domaines: Sciences du Vivant [q-bio]; Biochimie, Biologie Moléculaire

Michael Li, Hiren Patel, Armand Cognetta, Trever Smith, Ivy Mallick, et al.. Identification of cell wall synthesis inhibitors active against Mycobacterium tuberculosis by competitive activity-based protein profiling. Cell Chemical Biology, 2021, ⟨10.1016/j.chembiol.2021.09.002⟩. ⟨hal-03365089⟩