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Maternal, foetal and child consequences of immunosuppressive drugs during pregnancy in women with organ transplant: a review

Abstract : Although pregnancy remains exceptional in women after heart, liver or lung transplant, obstetricians and nephrologists are regularly confronted with pregnancy in renal transplant recipients. National and international registries have described the epidemiology of maternal, foetal and neonatal complications, and transplantation societies have published recommendations on the monitoring of these high-risk pregnancies. In this review, we summarize the existing data on maternal and foetal complications of pregnancies in women after renal transplant, especially the management of immunosuppression. We also describe the few available data on the middle- and long-term outcomes of their children who were exposed in utero to immunosuppressive drugs.
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https://hal.archives-ouvertes.fr/hal-03355311
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Submitted on : Monday, September 27, 2021 - 12:08:33 PM
Last modification on : Wednesday, March 30, 2022 - 2:40:12 PM

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Hugoline Boulay, Séverine Mazaud-Guittot, Jeanne Supervielle, Jonathan Maurice Chemouny, Virginie Dardier, et al.. Maternal, foetal and child consequences of immunosuppressive drugs during pregnancy in women with organ transplant: a review. Clinical Kidney Journal, Oxford University Press, 2021, 14 (8), pp.1871-1878. ⟨10.1093/ckj/sfab049⟩. ⟨hal-03355311⟩

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