Bayesian modeling of a bivariate toxicity outcome for early phase oncology trials evaluating dose regimens

Emma Gerard (1, 2) , Sarah Zohar (1, 2) , Christelle Lorenzato (3) , Moreno Ursino (1, 2) , Marie‐karelle Riviere (4)

1 HeKA - Health data- and model- driven Knowledge Acquisition
2 CRC (UMR_S_1138 / U1138) - Centre de Recherche des Cordeliers
3 Sanofi [Vitry-sur-Seine]
4 Sanofi Aventis R&D [Chilly-Mazarin]

Domaines: Statistiques [stat]; Sciences du Vivant [q-bio]

Emma Gerard, Sarah Zohar, Christelle Lorenzato, Moreno Ursino, Marie‐karelle Riviere. Bayesian modeling of a bivariate toxicity outcome for early phase oncology trials evaluating dose regimens. Statistics in Medicine, 2021, ⟨10.1002/sim.9113⟩. ⟨hal-03335297⟩