1-(4-Formyl-2,6-dimethoxyphenoxy)-4-chlorobut-2-yne

Jérôme Husson (1)

1 UTINAM - Univers, Transport, Interfaces, Nanostructures, Atmosphère et environnement, Molécules (UMR 6213)

A reaction of biomass-derived aldehyde synringaldehyde and half an equivalent of 1,4-dichlorobut-2-yne was attempted in order to obtain a bis-aldehyde with an alkyne spacer. The reaction was carried out in a basic media to effect bis O-alkylation, as described in literature for the preparation of structurally similar compounds. Nevertheless, only mono alkylation was observed.

Mots clés: O-alkylation; Williamson reaction; ether derivatives; alkyne derivatives

Domaines: Chimie; Planète et Univers [physics]

Jérôme Husson. 1-(4-Formyl-2,6-dimethoxyphenoxy)-4-chlorobut-2-yne. Molbank, 2021, 2021 (3), pp.M1252. ⟨10.3390/M1252⟩. ⟨hal-03330051⟩