Comparison of existing strategies for keeping symmetrical peaks in on-line Hydrophilic Interaction Liquid Chromatography x Reversed-Phase Liquid Chromatography despite solvent strength mismatch

Soraya Chapel (1) , Florent Rouvière (1) , Sabine Heinisch (1)

1 ISA-Chromatography & Hyphenated Techniques - Chromatographie et techniques couplées

Domaines: Chimie analytique

Soraya Chapel, Florent Rouvière, Sabine Heinisch. Comparison of existing strategies for keeping symmetrical peaks in on-line Hydrophilic Interaction Liquid Chromatography x Reversed-Phase Liquid Chromatography despite solvent strength mismatch. Journal of Chromatography A, 2021, 1642, pp.462001. ⟨10.1016/j.chroma.2021.462001⟩. ⟨hal-03318522⟩