A multipurpose integrated preclinical device for the treatment of glioblastoma

Khaled Metwally (1, 2) , Chiara Bastiancich (3) , Florian Correard (3, 4) , Anthony Novell (5) , Samantha Fernandez (6) , Benjamin Guillet (6, 7) , Benoit Larrat (8) , Serge Mensah (2) , Marie-Anne Estève (3, 4) , Anabela da Silva (1)

1 DiMABio - DiMABio
2 LMA - Laboratoire de Mécanique et d'Acoustique [Marseille]
3 INP - Institut de neurophysiopathologie
4 Service Pharmacie [Hôpital de la Timone - APHM]
5 BIOMAPS - LaBoratoire d'Imagerie biOmédicale MultimodAle Paris-Saclay
6 CERIMED - Centre Européen de Recherche en Imagerie médicale
7 C2VN - Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research
8 BAOBAB - Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields

A multipurpose integrated preclinical device that combines Blood-Brain Barrier permeabilization, Photo-Thermal Therapy (PTT) with photoacoustic thermometry, was developed as a novel preclinical versatile research instrument for the development of new PTT for Glioblastoma multiforme.

Mots clés: Photoacoustic; Glioblastoma; Thermal Energy

Domaines: Optique [physics.optics]; Cancer; Imagerie; Neurobiologie

Khaled Metwally, Chiara Bastiancich, Florian Correard, Anthony Novell, Samantha Fernandez, et al.. A multipurpose integrated preclinical device for the treatment of glioblastoma. European Conferences on Biomedical Optics OSA/SPIE (ECBO 2021), Jun 2021, Munich (virtual), Germany. ⟨10.1117/12.2614596⟩. ⟨hal-03313513⟩