An efficient and inexpensive method for functionalizing metallic biomaterials used in orthopedic applications

Soria Hamdaoui (1, 2) , Ambroise Lambert (1, 3) , Hafit Khireddine (2) , Rémy Agniel (1, 3) , Annelise Cousture (4, 3) , Régis Coulon , Olivier Gallet (1, 3) , Séverine Alfonsi (5, 3) , Mathilde Hindié (1, 3)

1 ERRMECe - Equipe de recherche sur les relations matrice extracellulaire-cellules
2 UB - Université Abderrahmane Mira [Université de Béjaïa] = University Abderrahmane Mira [University of Béjaïa]
3 I-MAT - Fédération INSTITUT DES MATÉRIAUX DE CERGY-PONTOISE
4 L2MGC - Laboratoire de mécanique et matériaux du génie civil
5 LPPI - Laboratoire de Physico-chimie des Polymères et des Interfaces

Implantations of metallic biomaterials are being carried out more and more frequently due to accident and population aging. Therefore, there is a need for new metallic implants which can combine properties such as durability, biocompatibility and affordability. In this study, multilayer functionalized 316 L stainless steel (SS) supports resistant to steam sterilization were presented. An electropolymerization of pyrrole was performed on SS supports to obtain a protective layer. This polypyrrole coating rendered SS surface resistant to corrosion. Then an electrodeposition of Calcium Phosphate (CaP) doped with increasing concentrations of silicon (Si) ranging from 0 to 2 mM was tested to improve support bone integration. The impacts of silicon addition in the CaP coating without or after steam sterilization were analyzed by profilometry, Scanning Electron Microscopy and Fourier Transform Infrared Spectroscopy. These latter revealed that CaP doped with 0.5 mM of Si constituted the optimal support formulation, presenting sterilization resistance and good biocompatibility.

Mots clés: 316 L stainless steel; Polypyrrole; Electrodeposition; Biomaterials; Calcium phosphate; Steam sterilization; STRO-1+ A pre-osteoblast

Domaines: Biomatériaux; Matériaux; Polymères

Soria Hamdaoui, Ambroise Lambert, Hafit Khireddine, Rémy Agniel, Annelise Cousture, et al.. An efficient and inexpensive method for functionalizing metallic biomaterials used in orthopedic applications. Colloid and Interface Science Communications, 2020, 37, pp.100282. ⟨10.1016/j.colcom.2020.100282⟩. ⟨hal-02901831⟩