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Article Dans Une Revue Flexible and Printed Electronics Année : 2018

Electronic Biosensing with Flexible Organic Transistor Devices

Caroline Kotlowski
  • Fonction : Auteur
Hadayat Ullah Khan
  • Fonction : Auteur
Ciril Reiner-Rozman
Josef Breu
  • Fonction : Auteur
Jang-Joo Kim
  • Fonction : Auteur
Zhenan Bao
  • Fonction : Auteur
Christoph Kleber
Paolo Pelosi
  • Fonction : Auteur
Wolfgang Knoll

Résumé

In this short review, we summarize the design and implementation of organic semiconducting materials-based field-effect transistors (OFETs) and the fabrication and use of reduced graphene-oxide field-effect transistors (rGO–FETs) as flexible transducers for electronic biosensing. We demonstrate that these platforms allow for the quantitative, in situ, and in real time monitoring of bio-affinity reactions between analytes from solution to the surface-immobilized receptors. The examples given include the binding of anti-bovine serum albumin (BSA) antibodies to their antigen, BSA, covalently attached to the channel of an OFET, or the reverse mode of operation, i.e., the binding of BSA from solution to the antibodies immobilized on a rGO transistor. Finally, we will discuss a few results obtained with odorant binding proteins used as receptors on a rGO–FET transducer for the realization of a biomimetic smell sensor
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Origine : Publication financée par une institution
Licence : CC BY - Paternité

Dates et versions

hal-03185607 , version 1 (11-07-2022)

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Paternité

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Caroline Kotlowski, Patrik Aspermair, Hadayat Ullah Khan, Ciril Reiner-Rozman, Josef Breu, et al.. Electronic Biosensing with Flexible Organic Transistor Devices. Flexible and Printed Electronics, 2018, 3 (3), pp.034003. ⟨10.1088/2058-8585/aad433⟩. ⟨hal-03185607⟩
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