The Usefulness of Phosphorus Compounds in Alkyne Synthesis

Frédéric Eymery (1) , Bogdan Iorga (1) , Philippe Savignac (1)

1 DCPH - Laboratoire Hétéroéléments et Coordination

Due to their versatility, β-keto ylides, α-halo ylides, diazomethylphosphonates, halomethylphosphonates and enolphosphates constitute a class of useful phosphorus reagents for the synthesis of alkynes. This review attempts to summarize their applications and focus on the role of each reagent as synthetic intermediates.

Mots clés: alkynes; β-keto ylides; thermal decomposition; α-halo ylides; diazomethylphosphonates; halomethylphosphonates; enol phosphates; 1; 1-or 1; 2-elimination

Domaines: Chimie organique

Frédéric Eymery, Bogdan Iorga, Philippe Savignac. The Usefulness of Phosphorus Compounds in Alkyne Synthesis. Synthesis: Journal of Synthetic Organic Chemistry, 2000, 2000 (02), pp.185-213. ⟨10.1055/s-2000-6241⟩. ⟨hal-03161387⟩