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Article Dans Une Revue Annals of Surgical Oncology Année : 2015

Quilting Suture of Mastectomy Dead Space Compared with Conventional Closure with Drain

Résumé

PURPOSE: This study was designed to compare conventional closure with a drain and quilting suture of mastectomy dead space for preventing wound seroma. METHODS: Consecutive patients undergoing mastectomy for breast cancer were included in this retrospective observational study. Patients received conventional closure with drainage or quilting suture for wound closure. Propensity score (PS) matching was performed based on potential confounders to minimize selection bias. The primary outcome was the rate of type 2 or 3 wound seroma according to the common terminology criteria for adverse events (CTCAE) definition. RESULTS: A total of 119 patients were included (quilting suture n = 59; conventional closure n = 60). Type 2 or 3 seroma was observed in 6.8 % of the quilting suture group and 21.7 % of the conventional closure group (crude odds ratio 0.26; 95 % confidence interval 0.08-0.86; p = 0.03). The overall seroma rate was 15.2 % in the quilting suture group and 51.7 % in the conventional closure group (p < 0.001). Persistent pain at days 15-21 was significantly less frequent in the quilting suture group than in the conventional suture group. PS matched analysis confirmed these findings, in particular the lower rate of type 2 or 3 seroma in the quilting suture group than in the conventional closure group (PS-matched odds ratio 0.16; 95 % confidence interval 0.04-0.72; p = 0.02). CONCLUSIONS: Quilting suture of the mastectomy dead space is associated with significantly less frequent seroma than conventional closure with drain.
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hal-03156119 , version 1 (02-03-2021)

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Lobna Ouldamer, Agnès Caille, Bruno Giraudeau, Gilles Body. Quilting Suture of Mastectomy Dead Space Compared with Conventional Closure with Drain. Annals of Surgical Oncology, 2015, 22 (13), pp.4233-4240. ⟨10.1245/s10434-015-4511-6⟩. ⟨hal-03156119⟩
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