Microwave-assisted synthesis of chromeno[2,3-d] pyrimidinone derivatives

Aida Chaker (1, 2) , Ennaji Najahi (2) , Françoise Nepveu (2) , Fakher Chanchoub (1)

1 Université de Sfax
2 PHARMA-DEV - Pharmacochimie et Biologie pour le Développement

New series of 10-anilino-9-alkyl-12-aryl-10,12-dihydro-11H-benzo[5,6] chromeno [2,3-d]pyrimidin-11-ones 5(a–e) and 9-anilino-10-alkyl-7-aryl-7,9-dihydro-8H-benzo[7,8]chromeno[2,3-d]pyrimidin-8-ones 6(a–f) were prepared in three steps with microwave irradiation. The procedure is easy, avoiding time-consuming syntheses is not costly.

Mots clés: Microwave irradiation; Chromeno[2; 3-d]pyrimidinones; Phenylhydrazine

Domaines: Chimie organique

Aida Chaker, Ennaji Najahi, Françoise Nepveu, Fakher Chanchoub. Microwave-assisted synthesis of chromeno[2,3-d] pyrimidinone derivatives. Arabian Journal of Chemistry, 2017, 10 (Supp 2), pp.S3040-S3047. ⟨10.1016/j.arabjc.2013.11.045⟩. ⟨hal-03149839⟩