Pheochromocytoma in a patient presenting with ventricular fibrillation and carotid dissection: a case report

Nicolas Lanot , Jérôme Adda , François Roubille (1, 2) , Mariama Akodad

1 PhyMedExp - Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046]
2 CHRU Montpellier - Centre Hospitalier Régional Universitaire [Montpellier]

Background: Pheochromocytoma is an endocrine tumour secreting catecholamines, most often revealed by clinical symptoms (headache, palpitations, diaphoresis, or resistant hypertension). Some cases of ventricular arrhythmias were described in the literature, without any formal link between arrhythmia and pheochromocytoma. Case summary: We report a case of pheochromocytoma discovered after cardiac arrest due to ventricular fibrillation in a 46-year-old patient. The diagnosis was suggested by clinical symptoms (headache, palpitation, and diaphoresis) and suspected on the abdominal computed tomography scan. The diagnosis was corroborated by metaiodobenzylguanidine scintigraphy and finally confirmed by anatomopathological analysis of the operative specimen. The cerebral imaging showed a dissection of the left internal carotid artery and an intraparenchymal haematoma that might be secondary to a catecholaminergic discharge of phaeochromocytoma and severe hypertension. Discussion: Since pheochromocytoma is accessible to curative treatment, its detection in case of cardiac arrest is essential to decrease the risk of arrhythmic recurrence.

Mots clés: Carotid dissection; Case report; Pheochromocytoma; Sudden cardiac death; Ventricular fibrillation

Domaines: Sciences du Vivant [q-bio]

Nicolas Lanot, Jérôme Adda, François Roubille, Mariama Akodad. Pheochromocytoma in a patient presenting with ventricular fibrillation and carotid dissection: a case report. European Heart Journal. Case Reports, 2021, 5 (2), ⟨10.1093/ehjcr/ytab012⟩. ⟨hal-03140068⟩